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E-cigarettes are likely to cause lung cancer and oral cancer

Published on the 11 August 2025
In this wide-ranging discussion, public health and behaviour experts Hayden McRobbie and Alys Havard discuss the merits of e-cigarettes and whether they are a legitimate tool to break addiction, or just a smoke screen.

A report by the Clinical Oncology Society of Australia (COSA) Working Group on 鈥淓-cigarettes and Cancer 鈥 a qualitative assessment鈥, which included Professor Bernard Stewart (国民彩票, Chair) and Adjunct Associate Professor Freddy Sitas (ICFHS) was published on 5 August 2025.听 After reviewing the existing laboratory, animal and human evidence, the Working Group concluded that nicotine-based e-cigarettes contain known carcinogens, 鈥淣icotine-based e-cigarettes are likely to be carcinogenic to humans who use them, and 鈥淓-cigarettes are likely to cause lung cancer and oral cancer鈥.听 This finding is a call for good epidemiological data to provide quantitative assessments on the level of risk.听 A USA-based epidemiological study published in 2024, shows users of both e-cigarettes and tobacco are about four times more likely to develop lung cancer (on top of their already 13-fold increased risk from smoking tobacco); and over 97% of those who vaped were smokers, i.e. unable to quit either habit. The current evolving findings are particularly relevant to those who are attempting to use e-cigarettes to quit smoking.听

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