国民彩票

Dr Megan Lenardon

Dr Megan Lenardon

Senior Lecturer
Science
School of Biotech & Biomolecular Science

I obtained a BSc (Hons) in Microbiology from 国民彩票 in 2000, before going on to complete a PhD in Molecular Genetics in 2005 under the supervision of Prof. Ian Dawes. I then moved to the world-renowned Aberdeen Fungal Group (AFG) at the University of Aberdeen in Scotland where I worked as a postdoctoral research fellow with Profs. Neil Gow and Al Brown. During my postdoctoral years, my research focussed on fungal call wall structure and biosynthesis, with a particular interest in the regulation of chitin synthesis during the growth of Candida albicans, as well as the immune recognition of fungal cell wall components, and 颁.听补濒产颈肠补苍蝉 stress responses. I set up my own group in the AFG in 2012 upon the receipt of a New Investigator award from the Medical Research Council (UK), and in 2017, returned to 国民彩票 as a Senior Lecturer in the School of Biotechnology and Biomolecular Sciences.

My research activities聽are focussed on translating my love of basic fungal cell biology to address the unmet needs in medical mycology in innovative ways.聽I am the convenor of the Eukaryotic Microbes Special Interest Group (SIG) of the Australian Society for Microbiology (ASM), a member of ASM NSW/ACT branch committee, an editorial board member of The Cell Surface聽and review grants for Australian, British, Canadian and French funding bodies.聽

Phone
(+612) 9385-1780
Location
School of Biotechnology and Biomolecular Sciences Office: Room 4103, Biosciences South Building (E26)
  • Book Chapters | 2013
    Hall RA; Lenardon MD; Alverez FJ; Nogueira FM; Mukaremera L; Gow NAR, 2013, 'The Candida albicans cell wall: structure and role in morphogenesis and immune recognition', in Mora-Montes HM (ed.), The fungal cell wall, Nova Science Publishers, New York, pp. 1 - 26,
  • Journal articles | 2025
    Dinh H; Fernandes KE; Erpf PE; Clay EJM; Tay AP; Nagy SS; Schaefer S; Maharjan R; Lenardon MD; Multari DH; Haynes PA; Paulsen IT; Santiago MJ; Connor M; Carter D; Cain AK, 2025, 'Uncovering the antifungal potential of Cannabidiol and Cannabidivarin', Plos Neglected Tropical Diseases, 19, pp. e0013081,
    Journal articles | 2025
    Giri A; Aquib M; Choudhury A; Kannaujiya VK; Lim JL; Gu Z; Lenardon MD; Boyer C, 2025, 'Lipoic Acid Based Redox-Responsive Degradable Antimicrobial Polymers', Macromolecular Rapid Communications,
    Journal articles | 2025
    Gmedhin H; Schaefer S; Corrigan N; Wu P; Gu Z; Lenardon MD; Boyer C, 2025, 'Effect of Defined Block Sequence Terpolymers on Antifungal Activity and Biocompatibility', Macromolecular Bioscience, 25,
    Journal articles | 2024
    McCrory C; Lenardon M; Traven A, 2024, 'Bacteria-derived short-chain fatty acids as potential regulators of fungal commensalism and pathogenesis', Trends in Microbiology, 32, pp. 1106 - 1118,
    Journal articles | 2024
    Schaefer S; Corrigan N; Brunke S; Lenardon MD; Boyer C, 2024, 'Combatting Fungal Infections: Advances in Antifungal Polymeric Nanomaterials', Biomacromolecules, 25, pp. 5670 - 5701,
    Journal articles | 2024
    Schaefer S; Melodia D; Corrigan N; Lenardon MD; Boyer C, 2024, 'Effect of Star Topology Versus Linear Polymers on Antifungal Activity and Mammalian Cell Toxicity', Macromolecular Bioscience, 24,
    Journal articles | 2024
    Schaefer S; Melodia D; Pracey C; Corrigan N; Lenardon MD; Boyer C, 2024, 'Mimicking Charged Host-Defense Peptides to Tune the Antifungal Activity and Biocompatibility of Amphiphilic Polymers', Biomacromolecules, 25, pp. 871 - 889,
    Journal articles | 2024
    Schaefer S; Vij R; Sprague JL; Austermeier S; Dinh H; Judzewitsch PR; M眉ller-Loennies S; Lopes Silva T; Seemann E; Qualmann B; Hertweck C; Scherlach K; Gutsmann T; Cain AK; Corrigan N; Gresnigt MS; Boyer C; Lenardon MD; Brunke S, 2024, 'A synthetic peptide mimic kills Candida albicans and synergistically prevents infection', Nature Communications, 15, pp. 1 - 22,
    Journal articles | 2023
    Gow NAR; Lenardon MD, 2023, 'Architecture of the dynamic fungal cell wall', Nature Reviews Microbiology, 21, pp. 248 - 259,
    Journal articles | 2022
    Ricci L; Mackie J; Donachie GE; Chapuis A; Mezerov谩 K; Lenardon MD; Brown AJP; Duncan SH; Walker AW, 2022, 'Human gut bifidobacteria inhibit the growth of the opportunistic fungal pathogen Candida albicans', FEMS Microbiology Ecology, 98, pp. fiac095,
    Journal articles | 2021
    Schaefer S; Pham TTP; Brunke S; Hube B; Jung K; Lenardon MD; Boyer C, 2021, 'Rational Design of an Antifungal Polyacrylamide Library with Reduced Host-Cell Toxicity', ACS Applied Materials and Interfaces, 13, pp. 27430 - 27444,
    Journal articles | 2021
    da Silva Dantas A; Nogueira F; Lee KK; Walker LA; Edmondson M; Brand AC; Lenardon MD; Gow NAR, 2021, 'Crosstalk between the calcineurin and cell wall integrity pathways prevents chitin overexpression in Candida albicans', Journal of Cell Science, 134, pp. jcs258889,
    Journal articles | 2020
    Lenardon MD; Sood P; Dorfmueller HC; Brown AJP; Gow NAR, 2020, 'Scalar nanostructure of the Candida albicans cell wall; a molecular, cellular and ultrastructural analysis and interpretation', Cell Surface, 6, pp. 100047,
    Journal articles | 2018
    Walker L; Sood P; Lenardon MD; Milne G; Olson J; Jensen G; Wolf J; Casadevall A; Adler-Moore J; Gow NAR, 2018, 'The viscoelastic properties of the fungal cell wall allow traffic of ambisome as intact liposome vesicles', Mbio, 9, pp. 10.1128/mbio.02383 - 10.1128/mbio.02317,
    Journal articles | 2017
    Sherrington SL; Sorsby E; Mahtey N; Kumwenda P; Lenardon MD; Brown I; Ballou ER; MacCallum DM; Hall RA, 2017, 'Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition', Plos Pathogens, 13, pp. e1006403,
    Journal articles | 2016
    Childers DS; Raziunaite I; Mol Avelar G; Mackie J; Budge S; Stead D; Gow NAR; Lenardon MD; Ballou ER; MacCallum DM; Brown AJP, 2016, 'The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence', Plos Pathogens, 12, pp. e1005566,
    Journal articles | 2015
    Preechasuth K; Anderson JC; Peck SC; Brown AJP; Gow NAR; Lenardon MD, 2015, 'Cell wall protection by the Candida albicans class I chitin synthases', Fungal Genetics and Biology, 82, pp. 264 - 276,
    Journal articles | 2014
    Wagener J; Malireddi RKS; Lenardon MD; K枚berle M; Vautier S; MacCallum DM; Biedermann T; Schaller M; Netea MG; Kanneganti TD; Brown GD; Brown AJP; Gow NAR, 2014, 'Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation', Plos Pathogens, 10, pp. e1004050,
    Journal articles | 2013
    Hall RA; Bates S; Lenardon MD; MacCallum DM; Wagener J; Lowman DW; Kruppa MD; Williams DL; Odds FC; Brown AJP; Gow NAR, 2013, 'The Mnn2 Mannosyltransferase Family Modulates Mannoprotein Fibril Length, Immune Recognition and Virulence of Candida albicans', Plos Pathogens, 9,
    Journal articles | 2013
    Walker LA; Lenardon MD; Preechasuth K; Munro CA; Gow NAR, 2013, 'Cell wall stress induces alternative fungal cytokinesis and septation strategies', Journal of Cell Science, 126, pp. 2668 - 2677,
    Journal articles | 2012
    Kaloriti D; Tillmann A; Cook E; Jacobsen M; You T; Lenardon M; Ames L; Barahona M; Chandrasekaran K; Coghill G; Goodman D; Gow NAR; Grebogi C; Ho HL; Ingram P; McDonagh A; De Moura APS; Pang W; Puttnam M; Radmaneshfar E; Romano MC; Silk D; Stark J; Stumpf M; Thiel M; Thorne T; Usher J; Yin Z; Haynes K; Brown AJP, 2012, 'Combinatorial stresses kill pathogenic Candida species', Medical Mycology, 50, pp. 699 - 709,
    Journal articles | 2012
    Lenardon MD; Nantel A, 2012, 'Rapid detection of aneuploidy following the generation of mutants in candida albicans', , 845, pp. 41 - 49,
    Journal articles | 2012
    You T; Ingram P; Jacobsen MD; Cook E; McDonagh A; Thorne T; Lenardon MD; De Moura AP; Romano MC; Thiel M; Stumpf M; Gow NAR; Haynes K; Grebogi C; Stark J; Brown AJP, 2012, 'A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi', BMC Research Notes, 5,
    Journal articles | 2011
    Cheng SC; van de Veerdonk FL; Lenardon M; Stoffels M; Plantinga T; Smeekens S; Rizzetto L; Mukaremera L; Preechasuth K; Cavalieri D; Kanneganti TD; van der Meer JWM; Kullberg BJ; Joosten LAB; Gow NAR; Netea MG, 2011, 'The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans', Journal of Leukocyte Biology, 90, pp. 357 - 366,
    Journal articles |